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Global analyst firm - Frost & Sullivan published their newest report on “Consumer Experience with Toxin Resistance” in Asia Pacific and included 2,441 Botulinum Toxin users who have taken at least 3 times, from the ages of 21 to 55 years old. There are 76% of Hong Kong respondents experienced a decline in treatment effects. With the high awareness and concern for Neutralizing Antibodies, the willingness of Hong Kong respondents to choose Botulinum Toxin Treatment product, that has High Purity+ with Zero Impurities* was highly increased.


of Hong Kong users have started to experience and acknowledge DIMINISHING EFFICACY with 3 or more cycles of Botulinum Toxin#

of Hong Kong users increased the knowledge of presence of impurities* in Botulinum Toxin might increase the risk of Neutralizing Antibody formation within body in past two years (Compared 2018 to 2021) #
of Hong Kong users willing to choose Botulinum Toxin Treatment product, that has High Purity+ with Zero Impurities*#

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Toxin Consumer Market Study

The Pure Toxin Xeomin with Zero impurities*(No complexing proteins), let’s get your beauty journey started.

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Understand the New Generation Botulinum Toxin

XEOMIN®(incobotulinumtoxinA) is a new generation, pure botulinum toxin, free from impurities*

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Ask the Expert

Learn about the experts say about XEOMIN® (incobotulinumtoxinA).

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XEOMIN® is approved by the US Food and Drug Administration (US FDA), UK MHRA, The Federal Institute for Drugs and Medical Devices in Germany and the Hong Kong Department of Health. A state-of-the-art purification process removes the unnecessary impurities*, providing only the purified active neurotoxin for treatment, with lower risk of antibody formation.


Introducing the pure toxin with zero impurities* and zero complexing proteins is a new generation highly purified Botulinum Toxin. It provides the full benefits of Botulinum Toxin with lower risk of antibody formation that may cause toxin resistance during treatment.


For all the benefits you can experience with Botulinum Toxin treatments, choose the Pure Toxin with Zero Impurities* as your lifetime aesthetic treatment that gives you natural and lasting results you desire.

Results within 2-4 days3

More than 98% of users are satisfied with XEOMIN® treatment results.4

# A consumer market study conducted on “Consumer Experience with Toxin Resistance” by Merz Aesthetics in partnership with Frost & Sullivan across 8 Asia Pacific Countries (Australia, Hong Kong, Indonesia, Singapore, South Korea, Taiwan, Philippine s and Thailand) and included 2,441 Botulinum toxin users from the ages of 21 to 55 years old.

^ Excluded the patients who experienced the BoutulinumToxin A treatment which as presence of impurities*

*Impurities refer to the presence of complexing proteins, inactive neurotoxin, flagellin and bacterial DNA contaminants.1,2

+Pure refers to the absence of complexing proteins, inactive neurotoxin, flagellin and bacterial DNA contaminants.1,2

1. Park JY et al. Neurotoxin impurities: A Review of threats to Efficacy. PlastRecontrSurg Glob Open. 2020;8(1):e2627

2. KerscherM, et al. IncobotulinumtoxinA: A Highly Purified and Precisely Manufactured Botulinum Neurotoxin Type A. J Drugs Dermatol. 2019 Jan 1;18(1):52-57

3. Prager W et al. Clin Intery Aging.2013; 8:449-456

4. ImhofM, et al. A Phase III Study of IncobotulinumtoxinAin the Treatment of Glabellar Frown Lines. J Clin AesthestDermatol. 2011;4(10):28-34.



Aesthetic Physician, UK
Dr. Goldie has been an aesthetic physician for 10 years and is the Medical Director of European Medical Aesthetics training, one of European largest training companies. Through Medics Direct, the UK training arm of this organization she has overseen the training of over 4000 medical professionals.
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PhD, Biochemist
Dr Jürgen Frevert could be described as the father of XEOMIN®. He first heard of the toxin more than 30 years ago, when, as a post-doctoral researcher, he was tasked with purifying botulinum toxin type A.
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PhD, Site Head of Merz Pharmaceuticals’ state-of-the-art production facility at Dessau, Germany
Michael Pfeil has been involved in the manufacture of XEOMIN® from day 1.
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German dermatologist Dr. Med. T. Walker has been using XEOMIN®clinically for more than a decade. With his wealth of experience, he explains in detail the medical cosmetic trends in Germany and Europe and the widespread use of botulinum toxin Fallacies, as well as the benefits of home-use type A pure botulinum toxin without complex proteins.
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Based on years of clinical experience, Dr Tatjana Pavicic, board member of the International Society for Derm Surgery, also explains how to properly use Type A botulinum toxin to reduce wrinkles and improve skin aging by analyzing facial dynamic and static patterns.
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